There is an old medical saying that just a few grains of thyroid hormone can make the difference between an idiot and an Einstein. It aptly characterizes the thyroid as a quickener of the tempo of life. All of the endocrine glands play remarkable roles in the body’s economy.
Deficiency of thyroid hormone may be due to lack of stimulation by the pituitary gland, defective hormone synthesis or impaired cellular conversion of T4 to T3 (often caused by mercury toxicity). The pituitary gland regulates thyroid activity through the secretion of thyroid-stimulating hormone (TSH). The combination of low thyroid hormone and elevated TSH blood levels usually indicates defective thyroid hormone synthesis, which is defined as primary hypothyroidism.
The enzyme thyroid peroxidase, converts T4 to T3 and is blocked by mercury in the body, primarily from dental mercury amalgam fillings and thimerosol, a mercury preservative found in vaccinations and other medicines. Genistein and daidzein from soy also inactivate thyroid peroxidase enzyme. In the case of T4 and T3, more than 99% is normally protein-bound in the blood. Less than 1% is free. Only the free hormone exerts biologic activity. The protein-bound hormone is inactive.
The influence of thyroid secretion on body processes and other organs is incredibly widespread and important. When the thyroid gland is removed from an otherwise normal animal, all metabolic activity is reduced. After removal of the thyroid gland, excess amounts of water, salts, and protein are retained within the body. Blood cholesterol also goes up.
People with type-O blood are said to be genetically prone to hypothyroidism and low levels of iodine. Approximately 46% of people are blood Type-O.
Excess thyroid causes higher energy levels, feeling too warm, and weight loss. The thyroid gland makes two versions of thyroid hormone from tyrosine and iodine.
Estrogen causes food calories to be stored as fat. Thyroid hormone causes fat calories to be turned into usable energy.
The daily dose of fluoride which people are now receiving in fluoridated communities (1.6 to 6.6 mg/day) actually exceeds the dose of fluoride found to depress the thyroid gland (2.3 to 4.5 mg/day). Hypothyroidism is currently one of the most common medical problems in the U.S. Synthroid, the drug doctors prescribe to treat hypothyroidism, was the fourth most prescribed drug in the U.S.
Symptoms of hypothyroidism include depression, fatigue, weight gain, muscle and joint pains, increased cholesterol levels and heart disease.
What was once known as fluoride-iodine antagonism can now be explained in detail by thousands of papers showing the fluoride power on G-protein activation. The biochemical activity of fluoride mimics TSH (thyroid-stimulating-hormone) on G-pr. Three-quarters of the world’s population is suffering from iodine deficiency in areas, which are identical to endemic fluorosis areas.. Fluoride was once used as an anti-thyroid medicine, prescribed by doctors in hospitals and clinics.
Following is a list of a few fluoride compounds whose anti-thyroid effects are established, and which are included in many of today’s medications, as well as in pesticides:3-fluoro-4-methoxy-phenylacetic acid; 3-fluoro-4-oxy-phenylacetic acid (Capacin); [p-fluorophenyl]-ethylketone; 3-fluoro-5-bromotyrosine; Iodofluorotyrosine; Fluorotyramine; 1-(3-fluoro-4-oxy) -phenyl-1-methyl-2-methyl-amino-ethane; 1-acetamino-2-fluoro-benzene-sulfonic-acid amide (fluorinated Prontalbin); Fluorphtiocol; Fluorobenzoic acid; Fluorotyrosine (Pardinon); PFOS (Scotchgard); perfluorooctance sulfonate; PFDA perfluorodecanoic acid; 1,1-dichloro-N-[(dimethylamino) sulfonyl]-1-fluoro-N-(4-methylphenyl) methanesulfenamide (Tolylfluanid); Fluoxetine (Prozac, Paxil); PMSF; Trifluoroiodomethane; Fluoroacetate; N-2-fluorenylacetamide; Trifluoperazine; Cyano(4-fluoro-3-phenoxyphenyl ) methyl 3-(2,2-dichloroethenyl)-2,2-dime thylcyclopropanecarboxylate; N-(4-fluorophenyl)-N-(1-methylet hyl)-2-[[5-(trifluoromethyl)- 1,3,4-thiadiazol-2-yl]oxy]acetami de (Pesticide Flufenacet – Bayer); N-(p-fluorophenyl)-6-[3-(trifluoro methyl)phenoxy]-2-pyridinecarbo xamide (Picolinafen); [R*,S*-(E)]-(±)-7-[3-(4-fluoroph enyl)-1-(1-methylethyl)-1H-indol- 2-yl]-3,5-dihydroxy-6-heptenoate (Fluvastatin); N-[4-cyano-3-(trifluoromethyl)ph enyl]-3-[(4-fluorophenyl)sulfonyl] -2-hydroxy-2-methyl-,(+ -) (Casodex – AstraZeneca); 8-chloro-6-(2-fluorophenyl) -1-methyl-4H-imidazo[1,5-a] [1,4]benzodiazepine (Midazolam); 1-(4-fluorophenyl)-3®-(3-(4-fluor ophenyl)-3(S)-hydroxypropyl)-4( S)- (4-hydroxyphenyl)-2-azetidinone (Ezetimibe – ZETIA).
Studies have shown an increased rate of heart disease due to atherosclerosis in individuals with hypothyroidism
Hypothyroidism can also cause hypertension, reduce the function of the heart and reduce heart rate. Nervous disorders, such as headaches, neurasthenia, mild psychic disturbances, especially affective disorders (depression), fears, anxieties, poor memory, and difficult concentration are frequently seen. Gastrointestinal symptoms are extremely common
Blood cholesterol is often elevated. If the cholesterol is elevated, it is a presumptive diagnosis of hypothyroidism.
Thyroxine controls all endocrine organs which is what we would expect if the thyroid controls the genome and also was the first to arrive in evolution and in fetal development.